The Molpure Advantage in ITLC: Optimized for Resolution

Thin-layer chromatography (TLC) is not a one-size-fits-all technique. At Molpure, our Instant Thin-Layer Chromatography (ITLC) plates are designed with specific applications in mind—optimizing separation efficiency, resolution, and consistency. Beyond standard SG or SA classifications, each plate is engineered to enhance performance and reproducibility for radiochemical analysis.

Beyond SG vs. SA

Most ITLC plates are classified as either:

• SG TLC: Silica gel-based, optimized for most radiochemical purity checks. It enables efficient separations using a polar stationary phase.
• SA TLC: Silicic acid-based, slightly acidic, and beneficial for basic and neutral  analytes that exhibit unique behavior under normal phase conditions.

But at Molpure, we go further.

Molpure ITLC: Designed for Targeted Performance

We understand that even within SG or SA, analytical needs vary. That’s why we use numerical product identifiers (e.g., SG TLC-100, SA TLC-500) to distinguish between unique formulations—each tailored to specific separation goals.

What makes each Molpure plate unique?

1. Stationary Phase Impregnation

Each plate features a precisely engineered level of silica gel or silicic acid impregnation, which directly affects separation characteristics, flow rate, and resolution.

We use intuitive symbols to represent impregnation levels:

Impregnation Level
Light
Medium
Heavy

(? = SG / ? = SA)

2. Membrane Characteristics

The glass microfiber base is equally critical. We optimize:

• Pore size
• Fiber density
• Flow dynamics

This ensures each plate delivers reproducible performance suited to the compounds you're analyzing.

Current Molpure ITLC Plate Options

Product Code	Type	Impregnation	Best For
SG TLC-100	Silica Gel	Light	Fast and efficient separations, low SG loading
SG TLC-400	Silica Gel	Medium	Balanced performance for general use
SA TLC-200	Silicic Acid	Light	Fastest run time, low SA loading
SA TLC-500	Silicic Acid	Medium	Analytes sensitive to mild acidity, fast run time
SA TLC-300	Silicic Acid	Heavy	High-resolution needs, slower run time than SA TLC-500

Each code represents a distinct formulation—not simply a concentration scale. It’s about matching the chemistry and physics of the plate to the demands of your assay.

Why Choose Molpure?

✔ More control over resolution and development time
✔ Tailored products for your exact application
✔ Greater reliability in high-stakes testing, including radiopharmaceutical QC

Whether you're looking for speed, precision, or reproducibility, there's a Molpure ITLC plate designed for your workflow.