ITLC Chromatography Strips for Radiopharmaceutical QC: Consistent Radiochemical Purity Across Applications
May 2nd 2026
Radiopharmaceutical quality control depends on accurate and reproducible radiochemical purity (% labeled) results. For nuclear pharmacies, switching chromatography media can be risky due to method validation requirements and workflow disruption.
Molpure ITLC SG and SA strips provide a practical solution by delivering comparable QC results without requiring SOP changes, making them an ideal alternative for routine radiopharmaceutical QC.
Comparable Radiochemical Purity Across Applications
Molpure ITLC strips are evaluated across a wide range of radiopharmaceuticals, including:
- Tc-99m MDP, DTPA, and PYP
- Tc-99m DMSA and Mebrofenin
- Tc-99m Sestamibi and Tetrofosmin
- Ga-68 DOTATATE (NetSpot®) and PSMA
No SOP Changes Required
One of the biggest advantages of Molpure ITLC SG and SA strips is their ability to function as a drop-in replacement:
- Compatible with existing mobile phases (acetone, saline, ethyl acetate, etc.)
- No method redevelopment required
- No retraining or workflow disruption
This allows labs to evaluate and implement Molpure with minimal operational risk.
Across these applications, results consistently show:
- Comparable % labeled values to standard ITLC methods
- Differences within expected analytical variability
- Reliable performance under routine QC conditions
Proven Performance in Real QC Workflows
Molpure ITLC strips have been used in real-world radiopharmacy environments across multiple applications. Performance data demonstrate:
- High radiochemical purity (typically ~97–99%)
- Consistent results across multiple trials
- Reliable separation behavior
These characteristics support their suitability for routine release testing.
Consistency and Reliability
Beyond comparable results, Molpure ITLC strips provide:
- Strong batch-to-batch reproducibility
- Reduced variability across trials
- Stable performance across different radiopharmaceutical kits
Consistency is critical in clinical QC—and Molpure is designed to deliver it.
Applications Supported
Molpure ITLC SG and SA strips support a broad range of QC workflows, including:
- Tc-99m bone, renal, cardiac, and hepatobiliary agents
- Ga-68 PET imaging compounds
- Antibody and peptide-based radiopharmaceuticals
Standard formats (0.7 × 6 cm and 1 × 8 cm) and compatibility with common solvents make them adaptable to existing methods.
Conclusion
Molpure ITLC SG and SA chromatography strips offer a reliable, low-risk alternative for radiopharmaceutical QC. With comparable radiochemical purity results and no need for SOP changes, they are designed to integrate seamlessly into routine workflows.
Proven. Reliable. Ready for your QC workflow.
Request a free sample and evaluate Molpure ITLC strips in your lab.